Effect of diet on experimental hypertension and on the development of polyarteritis nodosa in rats.
نویسندگان
چکیده
منابع مشابه
Pathogenesis of polyarteritis nodosa in hypertensive rats.
The pathogenesis of the vascular lesions of polyarteritis nodosa found in young rats with experimental renal hypertension is described. The panarteritic lesion was a product of the combination of renal injury and feeding sodium chloride. It began with a fibrinoid necrosis of the intima and media which was followed by an extensive inflammatory reaction with subsequent fibrosis of all layers of t...
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Polyarteritis nodosa is a necrotizing vasculitis of medium-sized arteries of unknown origin. Hypertension is present in 30% of patients with polyarteritis nodosa. In those cases, high renin levels are thought to be secondary to renal involvement. The present study was performed to identify causal factors of polyarteritis nodosa. In cyp1a1ren-2 transgenic rats, vasculitis of medium-sized arterie...
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Our report discusses a patient diagnosed with PAN since 3 years ago. He presented with fever, chills and nonproductive cough. He was a long time receiver of immunosuppressant drugs for his underlying condition. Upon examination he was febrile, had cushingoid appearance and cackles in both lungs. Lung CT scan showed opacities in right upper lobe lung and multiple bilateral nodules and ground gla...
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The responsiveness of hypophyseetomized female rats bearing pituitary autotransplants to chronic, low dosage treatment with desoxycorticosterone acetate was compared with that of intact females. Intact animals reacted rapidly, developed malignant hypertension, and died within 10 weeks. By contrast hypophysectomized autograft-bearing rats developed hypertension more slowly, and the majority of t...
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ورودعنوان ژورنال:
- Circulation research
دوره 3 1 شماره
صفحات -
تاریخ انتشار 1955